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1

Clinical lessons learned from the first leg of the CAR T cell journey

Majzner, Robbie G., Mackall, Crystal L.

Journal:

Nature Medicine

Year:

2019

Language:

english

File:

PDF, 1.97 MB

english, 2019

2

Neuroblastoma

Matthay, Katherine K., Maris, John M., Schleiermacher, Gudrun, Nakagawara, Akira, Mackall, Crystal L., Diller, Lisa, Weiss, William A.

Journal:

Nature Reviews Disease Primers

Year:

2016

Language:

english

File:

PDF, 6.11 MB

english, 2016

3

Simplified process for the production of anti–CD19-CAR–engineered T cells

Tumaini, Barbara, Lee, Daniel W., Lin, Tasha, Castiello, Luciano, Stroncek, David F., Mackall, Crystal, Wayne, Alan, Sabatino, Marianna

Journal:

Year:

2013

Language:

english

File:

PDF, 1004 KB

english, 2013

4

Programming CAR-T cells to kill cancer

Labanieh, Louai, Majzner, Robbie G., Mackall, Crystal L.

Journal:

Nature Biomedical Engineering

Year:

2018

Language:

english

File:

PDF, 5.04 MB

english, 2018

5

Prospects and Challenges for Use of CAR T Cell Therapies in Solid Tumors

Ramakrishna, Sneha, Barsan, Valentin, Mackall, Crystal

Journal:

Expert Opinion on Biological Therapy

Year:

2020

File:

PDF, 1.56 MB

2020

6

The Emerging Landscape of Immune Cell Therapies

Weber, Evan W., Maus, Marcela V., Mackall, Crystal L.

Journal:

Year:

2020

File:

PDF, 1.74 MB

2020

7

Immunologic, Virologic, and Neuropsychologic Responses in Human Immunodeficiency Virus-Infected Children Receiving Their First Highly Active Antiretroviral Therapy Regimen

Hazra, Rohan, Jankelevich, Shirley, Mackall, Crystal L., Avila, Nilo A., Wolters, Pamela, Civitello, Lucy, Christensen, Barbara, Jacobsen, Freda, Steinberg, Seth M., Yarchoan, Robert

Journal:

Viral Immunology

Year:

2007

Language:

english

File:

PDF, 250 KB

english, 2007

8

Myeloid cells in peripheral blood mononuclear cell concentrates inhibit the expansion of chimeric antigen receptor T cells

Stroncek, David F., Ren, Jiaqiang, Lee, Daniel W., Tran, Minh, Frodigh, Sue Ellen, Sabatino, Marianna, Khuu, Hanh, Merchant, Melinda S., Mackall, Crystal L.

Journal:

Year:

2016

Language:

english

File:

PDF, 272 KB

english, 2016

9

Activating Signals Dominate Inhibitory Signals in CD137L/IL-15 Activated Natural Killer Cells

Zhang, Hua, Cui, Yongzhi, Voong, Nga, Sabatino, Marianna, Stroncek, Dave F., Morisot, Sebastien, Civin, Curt I., Wayne, Alan S., Levine, Bruce L., Mackall, Crystal L.

Journal:

Journal of Immunotherapy

Year:

2011

Language:

english

File:

PDF, 462 KB

english, 2011

10

Elutriated lymphocytes for manufacturing chimeric antigen receptor T cells

Stroncek, David F., Lee, Daniel W., Ren, Jiaqiang, Sabatino, Marianna, Highfill, Steven, Khuu, Hanh, Shah, Nirali N., Kaplan, Rosandra N., Fry, Terry J., Mackall, Crystal L.

Journal:

Journal of Translational Medicine

Year:

2017

Language:

english

File:

PDF, 786 KB

english, 2017

11

New developments in immunotherapy for pediatric solid tumors

Schultz, Liora M., Majzner, Robbie, Davis, Kara L., Mackall, Crystal

Journal:

Current Opinion in Pediatrics

Year:

2017

Language:

english

File:

PDF, 703 KB

english, 2017

12

Engineering a designer immunotherapy

Mackall, Crystal L.

Journal:

Year:

2018

Language:

english

File:

PDF, 331 KB

english, 2018

13

Tumor Antigen Escape from CAR T-cell Therapy

Majzner, Robbie G., Mackall, Crystal L.

Journal:

Cancer Discovery

Year:

2018

Language:

english

File:

PDF, 2.66 MB

english, 2018

14

Thymic function in young/old chimeras: substantial thymic T cell regenerative capacity despite irreversible age-associated thymic involution

Crystal L. Mackall, Jennifer A. Punt, Paul Morgan, Andrew G. Farr, Ronald E. Gress

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 192 KB

english, 1998

15

Pilot trial of tumor-specific peptide vaccination and continuous infusion interleukin-2 in patients with recurrent Ewing sarcoma and alveolar rhabdomyosarcoma: An inter-institute NIH study

Ramzi Dagher, Lauren M. Long, Elizabeth J. Read, Susan F. Leitman, Charles S. Carter, Maria Tsokos, Theresa J. Goletz, Nilo Avila, Jay A. Berzofsky, Lee J. Helman, Crystal L. Mackall

Journal:

Pediatric Blood & Cancer

Year:

2002

Language:

english

File:

PDF, 136 KB

english, 2002

16

T-cell regeneration: all repertoires are not created equal

Crystal L. Mackall, Frances T. Hakim, Ronald E. Gress

Journal:

Immunology Today

Year:

1997

File:

PDF, 546 KB

1997

17

Adjuvant chemotherapy for the treatment of advanced pediatric nonrhabdomyosarcoma soft tissue sarcoma: The national cancer institute experience

Paul C. Nathan, Maria Tsokos, Lauren Long, Donna Bernstein, Leonard H. Wexler, Crystal L. Mackall, Lee J. Helman

Journal:

Pediatric Blood & Cancer

Year:

2005

Language:

english

File:

PDF, 89 KB

english, 2005

18

Effectiveness of chemotherapy in non-rhabdomyosarcoma soft tissue sarcomas—response

Paul C. Nathan, Lauren Long, Donna Bernstein, Crystal L. Mackall, Lee J. Helman, Maria Tsokos, Leonard H. Wexler

Journal:

Pediatric Blood & Cancer

Year:

2005

Language:

english

File:

PDF, 27 KB

english, 2005

19

Therapy for metastatic ESFT: Is it time to ask new questions?

Kristen M. Snyder, Crystal L. Mackall

Journal:

Pediatric Blood & Cancer

Year:

2007

Language:

english

File:

PDF, 65 KB

english, 2007

20

Metabolic syndrome traits in long-term survivors of pediatric sarcoma

Karen E. Hoffman, Joanne Derdak, Donna Bernstein, James C. Reynolds, Nilo A. Avila, Lynn Gerber, Seth M. Steinberg, George Chrousos, Crystal L. Mackall, Patrick J. Mansky

Journal:

Pediatric Blood & Cancer

Year:

2008

Language:

english

File:

PDF, 135 KB

english, 2008

21

Secondary supratentorial primitive neuroectodermal tumor following treatment of childhood osteosarcoma

Courtney D. Fitzhugh, Barbara Wise, Kristin Baird, Maria Tsokos, Lee Helman, Crystal Mackall, Sharon A. Savage, Katherine E. Warren

Journal:

Pediatric Blood & Cancer

Year:

2009

Language:

english

File:

PDF, 105 KB

english, 2009

22

Murine rhabdomyosarcoma is immunogenic and responsive to T-cell-based immunotherapy

Joanna L. Meadors, Yonghzi Cui, Qing-Rong Chen, Young K. Song, Javed Khan, Glenn Merlino, Maria Tsokos, Rimas J. Orentas, Crystal L. Mackall

Journal:

Pediatric Blood & Cancer

Year:

2011

Language:

english

File:

PDF, 736 KB

english, 2011

23

Persistent psychological distress in long-term survivors of pediatric sarcoma: the experience at a single institution

Lori Wiener, Haven Battles, Donna Bernstein, Lauren Long, Joanne Derdak, Crystal L. Mackall, Patrick J. Mansky

Journal:

Psycho-Oncology

Year:

2006

Language:

english

File:

PDF, 144 KB

english, 2006

24

Immune reconstitution prevents metastatic recurrence of murine osteosarcoma

Melinda S. Merchant, Fraia Melchionda, Manoj Sinha, Chand Khanna, Lee Helman, Crystal L. Mackall

Journal:

Cancer Immunology, Immunotherapy

Year:

2007

Language:

english

File:

PDF, 342 KB

english, 2007

25

Antigen loading of DCs with irradiated apoptotic tumor cells induces improved anti-tumor immunity compared to other approaches

Terry J. Fry, Jessica L. Shand, Matthew Milliron, Sarah K. Tasian, Crystal L. Mackall

Journal:

Cancer Immunology, Immunotherapy

Year:

2009

Language:

english

File:

PDF, 523 KB

english, 2009

26

Current concepts of thymic aging

Terry J. Fry, Crystal L. Mackall

Journal:

Seminars in Immunopathology

Year:

2002

Language:

english

File:

PDF, 237 KB

english, 2002

27

Thymic function in HIV infection

Rohan Hazra, Crystal Mackall

Journal:

Current HIV/AIDS Reports

Year:

2005

Language:

english

File:

PDF, 214 KB

english, 2005

28

Targeting pediatric malignancies for T cell-mediated immune responses

Crystal L. Mackall, Lee J. Helman

Journal:

Current Oncology Reports

Year:

2000

Language:

english

File:

PDF, 391 KB

english, 2000

29

Adolescents and young adults successfully restore lymphocyte homeostasis after intensive T-cell depleting therapy for cancer

Jessica C. Shand, Patrick J. Mansky, Margaret V. Brown, Thomas A. Fleisher, Crystal L. Mackall

Journal:

British Journal of Haematology

Year:

2006

Language:

english

File:

PDF, 466 KB

english, 2006

30

Pediatric large-volume leukapheresis: a single institution experience with heparin versus citrate-based anticoagulant regimens

Charles D. Bolan, Yu Ying Yau, Herbert C. Cullis, Mitchell E. Horwitz, Crystal L. Mackall, A. John Barrett, Harry L. Malech, Nadja N. Rehak, Alan S. Wayne, Susan F. Leitman

Journal:

Transfusion (Wiley)

Year:

2004

Language:

english

File:

PDF, 128 KB

english, 2004

31

Thymic aging and T-cell regeneration

Crystal L Mackall, Ronald E. Gress

Journal:

Immunological Reviews

Year:

1997

Language:

english

File:

PDF, 4.51 MB

english, 1997

32

Reply to “Is IL-7 from dendritic cells essential for the homeostasis of CD4+ T cells?”

Mackall, Crystal L, Guimond, Martin

Journal:

Nature Immunology

Year:

2010

Language:

english

File:

PDF, 173 KB

english, 2010

33

Harnessing the biology of IL-7 for therapeutic application

Mackall, Crystal L., Fry, Terry J., Gress, Ronald E.

Journal:

Nature Reviews Immunology

Year:

2011

Language:

english

File:

PDF, 866 KB

english, 2011

34

Perspective on Potential Clinical Applications of Recombinant Human Interleukin-7

Claude Sportès, Ronald E. Gress, Crystal L. Mackall

Journal:

Annals of the New York Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 409 KB

english, 2009

35

T-Cell Immunodeficiency Following Cytotoxic Antineoplastic Therapy: A Review

Crystal L. Mackall

Journal:

Year:

2000

Language:

english

File:

PDF, 149 KB

english, 2000

36

Autoimmunity during lymphopenia: A two-hit model

Tom Krupica Jr., Terry J. Fry, Crystal L. Mackall

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 162 KB

english, 2006

37

Harnessing the immune modulatory effects of IL7 for immunotherapy

Fraia Melchionda, Terry J. Fry, Crystal L. Mackall

Journal:

Clinical and Applied Immunology Reviews

Year:

2003

Language:

english

File:

PDF, 432 KB

english, 2003

38

Focus on sarcomas

Crystal L Mackall, Paul S Meltzer, Lee J Helman

Journal:

Year:

2002

Language:

english

File:

PDF, 167 KB

english, 2002

39

Restoration of T-cell homeostasis after T-cell depletion

Crystal L. Mackall, Frances T. Hakim, Ronald E. Gress

Journal:

Seminars in Immunology

Year:

1997

Language:

english

File:

PDF, 154 KB

english, 1997

40

Functional Outcomes and Life Satisfaction in Long-Term Survivors of Pediatric Sarcomas

Lynn H. Gerber, Karen Hoffman, Usha Chaudhry, Elizabeth Augustine, Rebecca Parks, Martha Bernad, Crystal Mackall, Seth Steinberg, Patrick Mansky

Journal:

Archives of Physical Medicine and Rehabilitation

Year:

2006

Language:

english

File:

PDF, 194 KB

english, 2006

41

Immune Reconstitution: From Stem Cells to Lymphocytes

Gay M. Crooks, Kenneth Weinberg, Crystal Mackall

Journal:

Biology of Blood and Marrow Transplantation

Year:

2006

Language:

english

File:

PDF, 76 KB

english, 2006

42

GVHD: A Continuing Barrier to the Safety of Allogeneic Transplantation

Pavan Reddy, Mukta Arora, Martin Guimond, Crystal L. Mackall

Journal:

Biology of Blood and Marrow Transplantation

Year:

2009

Language:

english

File:

PDF, 170 KB

english, 2009

43

NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biological Considerations of Hematological Relapse following Allogeneic Stem Cell Transplantation Unrelated to Graft-versus-Tumor Effects: State of the Science

Mitchell S. Cairo, Craig T. Jordan, Carlo C. Maley, Clifford Chao, Ari Melnick, Scott A. Armstrong, Warren Shlomchik, Jeff Molldrem, Soldano Ferrone, Crystal Mackall, Laurence Zitvogel, Michael R. Bis

Journal:

Biology of Blood and Marrow Transplantation

Year:

2010

Language:

english

File:

PDF, 742 KB

english, 2010

44

Reduced-Intensity Allogeneic Stem Cell Transplantation in Children and Young Adults with Ultrahigh-Risk Pediatric Sarcomas

Kristin Baird, Terry J. Fry, Seth M. Steinberg, Michael R. Bishop, Daniel H. Fowler, Cynthia P. Delbrook, Jennifer L. Humphrey, Alison Rager, Kelly Richards, Alan S. Wayne, Crystal L. Mackall

Journal:

Biology of Blood and Marrow Transplantation

Year:

2012

Language:

english

File:

PDF, 585 KB

english, 2012

45

Generation, Affinity Maturation, and Characterization of a Human Anti-Human NKG2D Monoclonal Antibody with Dual Antagonistic and Agonistic Activity

Ka Yin Kwong, Sivasubramanian Baskar, Hua Zhang, Crystal L. Mackall, Christoph Rader

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.42 MB

english, 2008

46

Demodicidosis in childhood acute lymphoblastic leukemia: An opportunistic infection occurring with immunosuppression

S.Percy Ivy, Crystal L. Mackall, Lia Gore, Ronald E. Gress, A.Howland Hartley

Journal:

The Journal of Pediatrics

Year:

1995

Language:

english

File:

PDF, 2.44 MB

english, 1995

47

T cell regeneration after chemotherapy: Implications for immunotherapy in the setting of minimal residual disease

Crystal L. Mackall, Frances T. Hakim, Thomas A. Fleisher, Margaret R. Brown, Dimiter S. Dimitrov, Ronald E. Gress

Journal:

European Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 129 KB

english, 1997

48

Bax Deficiency Partially Corrects Interleukin-7 Receptor α Deficiency

Annette R Khaled, Wen Qing Li, Jiaqiang Huang, Terry J Fry, Amr S Khaled, Crystal L Mackall, Kathrin Muegge, Howard A Young, Scott K Durum

Journal:

Year:

2002

Language:

english

File:

PDF, 546 KB

english, 2002

49

Neonates Support Lymphopenia-Induced Proliferation

Booki Min, Rebecca McHugh, Gregory D Sempowski, Crystal Mackall, Gilles Foucras, William E Paul

Journal:

Year:

2003

Language:

english

File:

PDF, 308 KB

english, 2003

50

Interleukin-7: master regulator of peripheral T-cell homeostasis?

Terry J. Fry, Crystal L. Mackall

Journal:

Trends in Immunology

Year:

2001

Language:

english

File:

PDF, 151 KB

english, 2001